Histone lactylation

Biomarker2 papers1 finding

Animals2

Interventions

1

Exercise

upin mice1Very low certainty

1 study

Exercise increases histone lactylation in mice.
Animals8-week
High-intensity interval training preferentially improves cardiac function via enhanced histone lactylation and macrophage polarization in SAMP8 mice · Experimental gerontology · 26 Aug 2026

Latest

3

bioRxivAnimalsPreprint21 Sep

MALDI-TOF imaging mass spectrometry demonstrates sex- and age-dependent spatial changes in brain energy metabolism in response to amyloid stress using a mouse model of Alzheimers Disease

Oxidative phosphorylation

Research SquareAnimalsPreprint18 Sep

Lactylation of histone variant MacroH2A1 at K134 regulates osteogenic differentiation of bone marrow mesenchymal stem cells

Stem cell differentiation

Experimental GerontologyAnimals26 Aug

High-intensity interval training preferentially improves cardiac function via enhanced histone lactylation and macrophage polarization in SAMP8 mice

High-intensity interval training