Renin-angiotensin-aldosterone system inhibitors

Intervention

3 papers2 findings

  • 1 lab in 1 country
  • 1 finding against
  • Humans2

Outcomes

1

Left ventricular dysfunction

no changein humans1HR 1.1

1 study
  1. Renin-angiotensin-aldosterone system inhibitors have no effect on left ventricular dysfunction in humans (HR 1.10, 95% CI 0.80–1.52).

    “this effect was not observed in the low-risk group (HR, 1.10; 95% CI, 0.80–1.52; p for interaction = 0.028; Figure 1).”

    Humansin AI-ECG low-risk group with baseline LVEF ≥ 50%median follow-up of 1,320 days

    Protective Effect of Renin–Angiotensin–Aldosterone System Inhibitors Guided by Artificial Intelligence–Enabled Electrocardiograms on Incident Left Ventricular Dysfunction: A Multicenter Cohort Study

    AHA Scientific Sessions 2025 abstract3 Nov 2025

More on Left ventricular dysfunction

Associations

1

Left ventricular dysfunction

downin humans1HR 0.7

1 study
  1. Renin-angiotensin-aldosterone system inhibitors lower the risk of left ventricular dysfunction in humans (HR 0.70, 95% CI 0.54–0.90).

    “In the high-risk group, ACEi or ARB therapy was associated with a lower risk of LVEF decline compared to no treatment (HR, 0.70; 95% CI, 0.54–0.90)”

    Humansin AI-ECG high-risk group with baseline LVEF ≥ 50%median follow-up of 1,320 days

    Protective Effect of Renin–Angiotensin–Aldosterone System Inhibitors Guided by Artificial Intelligence–Enabled Electrocardiograms on Incident Left Ventricular Dysfunction: A Multicenter Cohort Study

    AHA Scientific Sessions 2025 abstract3 Nov 2025

More on Left ventricular dysfunction

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