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Raspberry ketone

Intervention

2 papers study it6 findings

MeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Science and Technology Development Fund
  • Animals2

Outcomes

6

Body weight

downin rats1

1 study

  1. Raspberry ketone decreases body weight in rats.

    “Also, RK improved lipid profile parameters, liver enzymes and both body and liver tissue weights.”

    Animalsin HFFD-induced NAFLD ratsoralliver55 mg/kg/day8 weeksmalesn = 6

    Raspberry ketone ameliorates nonalcoholic fatty liver disease in rats by activating the AMPK pathway

    European journal of pharmacologyAug 19, 2023

AMPK signaling

upin rats1

1 study

  1. Raspberry ketone activates AMPK signaling in rats.

    “RK upregulated the expression of the phosphorylated AMP-activated protein kinase (P-AMPK)”

    Animalsin HFFD-induced NAFLD ratsoralliver55 mg/kg/day8 weeksmalesn = 6

    Raspberry ketone ameliorates nonalcoholic fatty liver disease in rats by activating the AMPK pathway

    European journal of pharmacologyAug 19, 2023

More on AMPK signaling

Nonalcoholic fatty liver disease

downin rats1

1 study

  1. Raspberry ketone decreases nonalcoholic fatty liver disease in rats.

    “Like CR, RK effectively attenuated NAFLD and ameliorated the changes attained by HFFD.”

    Animalsin HFFD-induced NAFLD ratsoralliver55 mg/kg/day8 weeksmalesn = 6

    Raspberry ketone ameliorates nonalcoholic fatty liver disease in rats by activating the AMPK pathway

    European journal of pharmacologyAug 19, 2023

More on Nonalcoholic fatty liver disease

Oxidative stress and ROS signaling

downin rats1

1 study

  1. Raspberry ketone decreases oxidative stress and ROS signaling in rats.

    “Either CR diet or RK reversed these changes and decreased HFFD-induced elevation of hepatic SphK1, S1P, S1PR1 and TLR4.”

    Animalshigh-fat-fructose-diet-induced NAFLDliver8 weeks

    Raspberry ketone improves non-alcoholic fatty liver disease induced in rats by modulating sphingosine kinase/sphingosine-1-phosphate and toll-like receptor 4 pathways

    The Journal of pharmacy and pharmacologyMay 11, 2023

More on Oxidative stress and ROS signaling

Inflammation

downin rats1

1 study

  1. Raspberry ketone decreases inflammation in rats.

    “Either CR diet or RK reversed these changes and decreased HFFD-induced elevation of hepatic SphK1, S1P, S1PR1 and TLR4.”

    Animalshigh-fat-fructose-diet-induced NAFLDliver8 weeks

    Raspberry ketone improves non-alcoholic fatty liver disease induced in rats by modulating sphingosine kinase/sphingosine-1-phosphate and toll-like receptor 4 pathways

    The Journal of pharmacy and pharmacologyMay 11, 2023

More on Inflammation

Non-alcoholic fatty liver disease

downin rats1

1 study

  1. Raspberry ketone decreases non-alcoholic fatty liver disease in rats.

    “Raspberry ketone improves non-alcoholic fatty liver disease induced in rats”

    Animalshigh-fat-fructose-diet-induced NAFLDoralliver55 mg/kg/day8 weeksn = 6

    Raspberry ketone improves non-alcoholic fatty liver disease induced in rats by modulating sphingosine kinase/sphingosine-1-phosphate and toll-like receptor 4 pathways

    The Journal of pharmacy and pharmacologyMay 11, 2023

More on Non-alcoholic fatty liver disease

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