R-phycocyanin
2 papers study it8 findings
- 1 lab in 1 country
- Model organisms2
Outcomes
7Lifespan
upin flies2
2 studies
Lifespan
upin flies2
R-phycocyanin extends lifespan in flies.
“Hence, the longevity activity of R-PC life was related with AMPK/mTOR/S6K autophagic signaling pathways in aging female drosophila melanogaster.”
Model organismsnatural agingfemales
International journal of biological macromoleculesJul 21, 2023
R-phycocyanin extends lifespan in flies.
“R-PC significantly increased the survival time and alleviated the oxidative stress of Drosophila melanogaster”
Model organismsnatural aging
Marine drugsJul 22, 2022
Inflammation
downin flies1
1 study
Inflammation
downin flies1
R-phycocyanin inhibits inflammation in flies.
“Meanwhile, R-PC significantly down-regulated TNF-α, MMP3, IL-1β, IL-6, IL-8 expression levels, and the anti-inflammatory and longevity was associated with R-PC-induced regulation of pI3k/AKT/FOXO3 signaling pathway in aging male drosophila melanogaster.”
Model organismsnatural agingmales
International journal of biological macromoleculesJul 21, 2023
Autophagy
upin flies1
1 study
Autophagy
upin flies1
R-phycocyanin induces autophagy in flies.
“The results showed that R-PC increased AMPK activity, thus enhanced the key regulatory factors of autophagy (Atg1, Atg8, Atg5), and consequently induced autophagy.”
Model organismsnatural agingfemales
International journal of biological macromoleculesJul 21, 2023
Lipid peroxidation
downin flies1
1 study
Lipid peroxidation
downin flies1
R-phycocyanin inhibits lipid peroxidation in flies.
“inhibited lipid peroxidation by enhancing the expressions of the endogenous stress marker genes”
Model organismsnatural aging
Marine drugsJul 22, 2022
Oxidative stress and ROS signaling
downin flies1
1 study
Oxidative stress and ROS signaling
downin flies1
R-phycocyanin decreases oxidative stress and ROS signaling in flies.
“alleviated the oxidative stress of Drosophila melanogaster”
Model organismsnatural aging
Marine drugsJul 22, 2022
Cell cycle regulation
downin human cells1
1 study
Cell cycle regulation
downin human cells1
R-phycocyanin prevents cell cycle regulation in human cells.
“R-PC prevented the H2O2-induced HUVEC cell cycle phase arrest”
CellsH2O2-induced
Marine drugsJul 22, 2022
Apoptosis
downin human cells1
1 study
Apoptosis
downin human cells1
R-phycocyanin protects against apoptosis in human cells.
“exhibiting a protective effect against H2O2-induced apoptotic HUVEC cells death”
CellsH2O2-induced
Marine drugsJul 22, 2022