Partial hepatectomy
1 paper1 finding
- 1 lab in 1 country
- 2 trials
- Funder: National Institute of Diabetes and Digestive and Kidney Diseases
- 1 of 1 finding with company ties
- Animals1
Outcomes
1Hepatocyte cell identity
upin animals1
1 study
Hepatocyte cell identity
upin animals1
Partial hepatectomy improves hepatocyte cell identity.
“Partial hepatectomy, associated with induced proliferation, restores identity of HIRA knockout livers with compensatory deposition of canonical histones H3.1/2.”
AnimalsHIRA knockout liversliver
HIRA-mediated H3.3 deposition preserves hepatocyte cell identity during liver aging
bioRxiv (Cold Spring Harbor Laboratory)11 Mar 2026Preprint
Trial sponsors
ECOG-ACRIN Cancer Research Group
1 trialPhase 2/3186 people
1 trialPhase 226 people
Funding
1 grantNational Institute of Diabetes and Digestive and Kidney DiseasesUS$88.9k
Latest
1 in 12 monthsbioRxiv
HIRA-mediated H3.3 deposition preserves hepatocyte cell identity during liver aging
Preprint: experiments in animalsMechanisms