OSM-neutralizing antibody

1 paper2 findings

1 lab in 1 country

Funders: National Natural Science Foundation of China and 2 more

Animals1

Outcomes

2

Ventricular contractility

upin mice1

1 study

OSM-neutralizing antibody improves ventricular contractility in mice.
“Therapeutic OSM neutralization in vivo similarly mitigated myocardial inflammation and fibrosis while preserving ventricular contractility.”
Animalsin EAM miceheart
Rapamycin preserves cardiac function in autoimmune myocarditis by reprogramming Cxcl9⁺ macrophages via the mTORC1-C/EBPβ-OSM axis
Redox biology13 Dec 2025

Myocardial inflammation

downin mice1

1 study

OSM-neutralizing antibody decreases myocardial inflammation in mice.
“Therapeutic OSM neutralization in vivo similarly mitigated myocardial inflammation and fibrosis while preserving ventricular contractility.”
Animalsin EAM miceheart
Rapamycin preserves cardiac function in autoimmune myocarditis by reprogramming Cxcl9⁺ macrophages via the mTORC1-C/EBPβ-OSM axis
Redox biology13 Dec 2025

Latest

1 in 12 months

Redox Biology19 Dec

Rapamycin preserves cardiac function in autoimmune myocarditis by reprogramming Cxcl9⁺ macrophages via the mTORC1-C/EBPβ-OSM axis

Experiments in miceRapamycin