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Nomilin

Intervention

2 papers3 findings

PubChemChEBIMeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Fok Ying Tung Education Foundation and 5 more
  • Animals1

Outcomes

2

Lifespan

upin mice1upin worms1

1 study

  1. Nomilin extends lifespan in mice.

    “Finally, dietary nomilin supplementation improved healthspan and lifespan in D-galactose- and doxorubicin-induced senescent mice as well as in male senescence accelerated mice prone 8 (SAMP8) mice”

    Animalsin D-galactose- and doxorubicin-induced senescent mice as well as in male senescence accelerated mice prone 8 (SAMP8) mice

    Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions

    Nature communications8 Jun 2023

  2. Nomilin extends lifespan in worms.

    “nomilin, a bitter-taste limoloid that is enriched in citrus, significantly extended the animals' lifespan, healthspan, and toxin resistance.”

    Model organisms

    Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions

    Nature communications8 Jun 2023

Healthspan

upin mice1

1 study

  1. Nomilin improves healthspan in mice.

    “dietary nomilin supplementation improved healthspan and lifespan in D-galactose- and doxorubicin-induced senescent mice as well as in male senescence accelerated mice prone 8 (SAMP8) mice”

    Animalsin D-galactose- and doxorubicin-induced senescent mice as well as in male senescence accelerated mice prone 8 (SAMP8) mice

    Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions

    Nature communications8 Jun 2023

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