Nitroglycerin

InterventionApproved 1981

1 paper studies it11 more mention it1 finding

PubChemChEBIMeSH

  • 1 lab in 1 country
  • 64 trials, none about aging, 26 with no results posted
  • Funders: National Heart, Lung, and Blood Institute and 2 more
  • Human trial1

Outcomes

1

Arterial diameter

upin humans1

1 study
  1. Nitroglycerin increases arterial diameter in humans (0.29-0.35 mm).

    “In the PA, compared with zero, NTG significantly increased diameter in all groups”

    Human trialsublingualpopliteal artery0.8 mg

    Preserved endothelium-independent vascular function with aging in men and women: evidence from the peripheral and cerebral vasculature

    Journal of applied physiology (Bethesda, Md. : 1985)Jun 30, 2023

Trials

0 about aging, of 64

Approved

All 14

Repurposing

All 30

In trials

  • Stable Angina

    Phase 4Status unknown3 trials

  • Chronic renal insufficiency

    Phase 4Results posted1 trial

  • Raynaud Disease

    Phase 3Completed4 trials

  • Diffuse Scleroderma

    Phase 3Completed3 trials

  • Fissure in Ano

    Phase 3Results posted3 trials

  • Spasm

    Phase 3Results posted2 trials

All 7
  • Hyperlipidemias

    Phase 3Results posted1 trial

Stopped

  • NCT03304496SuspendedCoronary artery disease

    The sample was not completed.

  • NCT01210378TerminatedNon small cell lung carcinoma

    Accrual stopped

  • NCT01811693TerminatedStroke

    The funding period for the study has ended.

Trial sponsors

Funding

1 grant since 2018

National Institute on AgingUS$1.1m

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 1Oct 2026: 01 paper in 12 months