Hemorrhagic shock

1. NAD+ precursors decrease hemorrhagic shock in Rodentia.

   “Treatments with polyphenol resveratrol and with nicotinamide adenine dinucleotide (NAD) precursors have both shown promising results in rodent models of hemorrhagic shock and resuscitation.”

   Reviewhemorrhagic shock and resuscitation

   Longevity pathways in stress resistance: targeting NAD and sirtuins to treat the pathophysiology of hemorrhagic shock

   GeroScience·18 Jan 2021

More on NAD+ precursors

1. Resveratrol decreases hemorrhagic shock in Rodentia.

   “Treatments with polyphenol resveratrol and with nicotinamide adenine dinucleotide (NAD) precursors have both shown promising results in rodent models of hemorrhagic shock and resuscitation.”

   Reviewhemorrhagic shock and resuscitation

   Longevity pathways in stress resistance: targeting NAD and sirtuins to treat the pathophysiology of hemorrhagic shock

   GeroScience·18 Jan 2021

More on Resveratrol

1. Hemorrhagic shock increases P21V1 expression in mice.

   “an upregulation of p21v1 was observed following hemorrhagic shock injury”

   Animalshemorrhagic shock injury

   p53 dependence of senescence markers p21v1 and p21v2 in aging and acute injury

   npj aging·14 Oct 2024

More on P21V1 expression