Pancreatitis
Disease6 papers1 finding
- Humans2
Effects
1Lipid Age Acceleration
upin humans1
1 study
Lipid Age Acceleration
upin humans1
Pancreatitis increases Lipid Age Acceleration in humans (mean LAA 2.71 years).
Humansin pancreatitis patients relative to healthy individualsserum
A Pathology-Trained Lipid Aging Clock Reveals Accelerated Aging and Prognostic Sphingolipid Signatures in Pancreatic Disease · Aging and disease · 1 Sep 2026
Trial sponsors
Masonic Cancer Center, University of Minnesota
1 trialPhase 483 people
Funding
National Institute of Diabetes and Digestive and Kidney DiseasesUS$1m3 grants since 2020
University of Minnesota Clinical Center for the Study of Acute Pancreatitis and Diabetes
National Institute of Diabetes and Digestive and Kidney DiseasesUniversity of MinnesotaUS$492.8k2020–2030
Dietary Predictors of New-Onset Diabetes following Acute Pancreatitis in the DREAM Study.
National Institute of Diabetes and Digestive and Kidney DiseasesPennsylvania State Univ Hershey Med CtrUS$162.5k2024–2028
National Institute of Diabetes and Digestive and Kidney DiseasesUniversity of California Los AngelesUS$354.8k2023–2027
Latest
120Y chromosome loss linked to advanced pancreatic cancer
Across two cohorts, about 50% of male patients with pancreatic ductal adenocarcinoma had lost the Y chromosome, an alteration enriched in advanced…Across two cohorts, about 50% of male patients with pancreatic ductal adenocarcinoma had lost the Y chromosome, an alteration enriched in advanced disease.
Model estimates pancreatic cancer risk in type 2 diabetes
At six months, the model’s ability to distinguish cancer cases from non-cases scored 0.88 in development, 0.89 in internal validation and 0.86 in…At six months, the model’s ability to distinguish cancer cases from non-cases scored 0.88 in development, 0.89 in internal validation and 0.86 in external validation.
Aged mice had high levels of a hormone that raises blood sugar
Experiments found increased release of the hormone in aged mice with normal or reduced responses to insulin, which lowers blood sugar.Experiments found increased release of the hormone in aged mice with normal or reduced responses to insulin, which lowers blood sugar.