Night-shift work

1. Night-shift work is associated with breast cancer in humans (OR 1.75, 95% CI 1.00 to 3.06).

   HumansCompared with never exposure to night shift workbreast≥20 yearsfemalesn = 1,719

   Mammographic density as a potential mediator in the association between night shift work and breast cancer risk · Occupational and environmental medicine · 5 Oct 2026

Breast cancer →

1. Night-shift work raises the risk of type 2 diabetes in humans (HR 1.16 (1.03 to 1.31)).

   Humanscompared with never working night shifts

   Occupations and work-related factors in relation to the incidence of type 2 diabetes: an exploratory study among 274,662 Dutch workers · BMJ public health · 21 Sep 2026

Type 2 diabetes →

1. Night-shift work raises the risk of obesity in humans (OR 1.62, 95% CI 1.33–1.99).

   Humanscompared to day workers

   Association of night shift work and related risk factors with overweight and obesity across Europe: the SHIFT2HEALTH Online Survey · Obesity facts · 12 Sep 2026

Obesity →

1. Night-shift work raises the risk of cardiometabolic risk in humans.

   Review

   Long-term night shift work and cardiometabolic health in healthcare workers: a review of mechanisms and precision intervention strategies · Frontiers in public health · 3 Sep 2026

1. Night-shift work is associated with endothelial function in humans (-0.054).

   Review

   Night Shift Work and Vascular Function Parameters: A Systematic Review of Occupational and Healthcare Evidence with Implications for Radiographers · F1000Research · 30 Jun 2026

Endothelial function →

1. Night-shift work is associated with arterial stiffness in humans (+1.29 m/s over 3 years).

   Review3 years

   Night Shift Work and Vascular Function Parameters: A Systematic Review of Occupational and Healthcare Evidence with Implications for Radiographers · F1000Research · 30 Jun 2026

Arterial stiffness →