Nerol

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Animals1

Outcomes

Mitochondrial fission and fusion

downin rats1

1 study

Nerol inhibits mitochondrial fission and fusion in rats.
“suppressed DRP1/FIS1-mediated abnormal mitochondrial fission”
Animalsin vascular dementia (2-VO) modelhippocampus8 weeks
Nerol ameliorates cognitive dysfunction in vascular dementia rats by inhibiting mitochondrial oxidative stress and reducing hippocampal senescence
Brain research bulletin29 Jan 2026

More on Mitochondrial fission and fusion

Hippocampal neuronal structural damage

downin rats1

1 study

Nerol decreases hippocampal neuronal structural damage in rats.
“alleviated hippocampal neuronal structural damage and dendritic degeneration”
Animalsin vascular dementia (2-VO) modelhippocampus8 weeks
Nerol ameliorates cognitive dysfunction in vascular dementia rats by inhibiting mitochondrial oxidative stress and reducing hippocampal senescence
Brain research bulletin29 Jan 2026

Cellular senescence

downin rats1

1 study

Nerol decreases cellular senescence in rats.
“nerol reduced the number of senescence-associated β-galactosidase-positive and TUNEL-positive cells”
Animalsin vascular dementia (2-VO) modelhippocampus8 weeks
Nerol ameliorates cognitive dysfunction in vascular dementia rats by inhibiting mitochondrial oxidative stress and reducing hippocampal senescence
Brain research bulletin29 Jan 2026

Latest

1 in 12 months

Brain Research Bulletin1 Feb

Nerol ameliorates cognitive dysfunction in vascular dementia rats by inhibiting mitochondrial oxidative stress and reducing hippocampal senescence

Experiments in ratsCognitive dysfunction

Paper

Nerol

Outcomes

Latest

Nerol ameliorates cognitive dysfunction in vascular dementia rats by inhibiting mitochondrial oxidative stress and reducing hippocampal senescence

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