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Nanofiber bundle scaffold incorporating ceria nanoparticles

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1

Outcomes

4

Apoptosis

downin rat cells1

1 study

  1. Nanofiber bundle scaffold incorporating ceria nanoparticles decrease apoptosis in rat cells.

    “alleviating senescence and apoptosis of TDSCs, downregulating the secretion of senescence-associated secretory phenotype (SASP)”

    Cellsunder oxidative stresstendon

    Energy-Supporting Enzyme-Mimic Nanoscaffold Facilitates Tendon Regeneration Based on a Mitochondrial Protection and Microenvironment Remodeling Strategy

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)Aug 24, 2022

More on Apoptosis

Cellular senescence

downin rat cells1

1 study

  1. Nanofiber bundle scaffold incorporating ceria nanoparticles decrease cellular senescence in rat cells.

    “alleviating senescence and apoptosis of TDSCs, downregulating the secretion of senescence-associated secretory phenotype (SASP)”

    Cellsunder oxidative stresstendon

    Energy-Supporting Enzyme-Mimic Nanoscaffold Facilitates Tendon Regeneration Based on a Mitochondrial Protection and Microenvironment Remodeling Strategy

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)Aug 24, 2022

More on Cellular senescence

Oxidative stress and ROS signalling

downin rats1

1 study

  1. Nanofiber bundle scaffold incorporating ceria nanoparticles decrease oxidative stress and ROS signalling in rats.

    “NBS@CeO reduces oxidative damage and accelerates structural regeneration of collagen fibers”

    Animalsin a rat Achilles tendon defect modelAchilles tendon

    Energy-Supporting Enzyme-Mimic Nanoscaffold Facilitates Tendon Regeneration Based on a Mitochondrial Protection and Microenvironment Remodeling Strategy

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)Aug 24, 2022

More on Oxidative stress and ROS signalling

Motor function

upin rats1

1 study

  1. Nanofiber bundle scaffold incorporating ceria nanoparticles improve motor function in rats.

    “NBS@CeO reduces oxidative damage and accelerates structural regeneration of collagen fibers, manifesting as recovering mechanical properties and motor function.”

    Animalsin a rat Achilles tendon defect modelAchilles tendon

    Energy-Supporting Enzyme-Mimic Nanoscaffold Facilitates Tendon Regeneration Based on a Mitochondrial Protection and Microenvironment Remodeling Strategy

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)Aug 24, 2022

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