Mmbox-loaded rapamycin hydrogel scaffold

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: National Health and Family Planning Commission of the People's Republic of China and 2 more
  • Animals1

Outcomes

2

Cellular senescence

downin rats1

1 study
  1. Mmbox-loaded rapamycin hydrogel scaffold decreases cellular senescence in rats.

    “Furthermore, it attenuates SME-associated chronic inflammation and cellular senescence, and promotes bone regeneration in the aged rat calvarial defect model.”

    Animalsaged rat calvarial defect modelcalvarium

    A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair

    Bioactive materials27 Feb 2026

More on Cellular senescence

Bone regeneration

upin rats1

1 study
  1. Mmbox-loaded rapamycin hydrogel scaffold improves bone regeneration in rats.

    “Furthermore, it attenuates SME-associated chronic inflammation and cellular senescence, and promotes bone regeneration in the aged rat calvarial defect model.”

    Animalsaged rat calvarial defect modelcalvarium

    A multimodal ROS logic-gated therapeutic platform disrupts the vicious cycle of senescence to promote aged bone defect repair

    Bioactive materials27 Feb 2026

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