ML385
Intervention2 papersPubChem 1383822
- Animals2
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2AnimalsPeer-reviewed
4-Octyl itaconate restores parotid gland function in aging mice
The itaconate derivative reduces fibrosis and lipid buildup while curbing oxidative stress through AMPK signaling pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · Chen Y et al.
Activating Sirt1 reduces aortic valve calcification in mice and human cells
The sirtuin protects valves by activating the Nrf2 pathway, preserving mitochondrial function, and preventing iron-driven ferroptosis.
International journal of molecular medicine · Yan F et al.