Krill oil

Intervention

4 papers10 findings

  • 4 independent labs in 2 countries
  • Funders: Central Michigan University and 4 more
  • Human trial1
  • Animals3

Outcomes

10

Handgrip strength

upin humans1

1 study
  1. Krill oil improves handgrip strength in humans (-0.2 ± 0.5 kg vs -0.9 ± 0.7 kg).

    “KO supplementation during body weight loss attenuates the decline in FFM and muscle strength.”

    Human trialduring alternate-day fasting8 weeksn = 41

    Benefits of Krill Oil Supplementation During Alternate-Day Fasting in Adults With Overweight and Obesity: A Randomized Trial

    Obesity (Silver Spring, Md.)16 Jul 2025

Fat-free mass

downin humans1

1 study
  1. Krill oil prevents fat-free mass in humans (-0.2 ± 0.9 kg vs -1.2 ± 2.0 kg).

    “Changes in FFM and HGS were different (p < 0.05) between groups.”

    Human trialduring alternate-day fasting8 weeksn = 41

    Benefits of Krill Oil Supplementation During Alternate-Day Fasting in Adults With Overweight and Obesity: A Randomized Trial

    Obesity (Silver Spring, Md.)16 Jul 2025

Body weight

no changein humans1

1 study
  1. Krill oil has no effect on body weight in humans (-4.6 ± 1.4 kg vs -4.5 ± 1.9 kg).

    “Body weight reduction was not different (p > 0.05) between groups (KO, -4.6 ± 1.4 kg; Placebo, -4.5 ± 1.9 kg).”

    Human trialduring alternate-day fasting8 weeksn = 41

    Benefits of Krill Oil Supplementation During Alternate-Day Fasting in Adults With Overweight and Obesity: A Randomized Trial

    Obesity (Silver Spring, Md.)16 Jul 2025

Synaptic density

no changein rats1

1 study
  1. Krill oil has no effect on synaptic density in rats.

    “However, KO supplementation did not produce significant changes in the other quantified parameters.”

    AnimalsControl and high-fat dietscortex and hippocampus12 weeks

    New Insights on the Effects of Krill Oil Supplementation, a High-Fat Diet, and Aging on Hippocampal-Dependent Memory, Neuroinflammation, Synaptic Density, and Neurogenesis

    International journal of molecular sciences28 Oct 2024

neurogenesis

no changein rats1

1 study
  1. Krill oil has no effect on neurogenesis in rats.

    “However, KO supplementation did not produce significant changes in the other quantified parameters.”

    AnimalsControl and high-fat dietscortex and hippocampus12 weeks

    New Insights on the Effects of Krill Oil Supplementation, a High-Fat Diet, and Aging on Hippocampal-Dependent Memory, Neuroinflammation, Synaptic Density, and Neurogenesis

    International journal of molecular sciences28 Oct 2024

Inflammation

no changein rats1

1 study
  1. Krill oil has no effect on inflammation in rats.

    “However, KO supplementation did not produce significant changes in the other quantified parameters.”

    AnimalsControl and high-fat dietscortex and hippocampus12 weeks

    New Insights on the Effects of Krill Oil Supplementation, a High-Fat Diet, and Aging on Hippocampal-Dependent Memory, Neuroinflammation, Synaptic Density, and Neurogenesis

    International journal of molecular sciences28 Oct 2024

More on Inflammation

Spatial memory

no changein rats1

1 study
  1. Krill oil has no effect on spatial memory in rats.

    “However, KO supplementation did not produce significant changes in the other quantified parameters.”

    AnimalsControl and high-fat diets12 weeks

    New Insights on the Effects of Krill Oil Supplementation, a High-Fat Diet, and Aging on Hippocampal-Dependent Memory, Neuroinflammation, Synaptic Density, and Neurogenesis

    International journal of molecular sciences28 Oct 2024

Lung cancer

upin mice1

1 study
  1. Krill oil increases lung cancer in mice (8.2-fold).

    “Lovaza and krill oil significantly increased lung tumors (4.1- and 8.2-fold) and hemorrhagic diathesis (3.9- and 3.1-fold).”

    Animalsmales

    Dietary supplementation with Lovaza and krill oil shortens the life span of long-lived F1 mice

    Age (Dordrecht, Netherlands)10 May 2014

More on Lung cancer

Lifespan

downin mice1−4.7% median lifespan

1 study
  1. Krill oil shortens lifespan in mice (-4.7% median lifespan).

    “Lovaza and krill oil non-significantly shortened median life span by 9.8 and 4.7 %, respectively.”

    Animals1.17 g oil/kg dietmales

    Dietary supplementation with Lovaza and krill oil shortens the life span of long-lived F1 mice

    Age (Dordrecht, Netherlands)10 May 2014

CAT

upin mice1

1 study
  1. Krill oil increases CAT in mice (P < 0.001).

    “significantly higher (P < 0.001) activities and expression of CAT, GSH-Px and SOD”

    Animalsin 6.5-month-old female B/W mice compared to CO-fed miceliver10% (w/w)females

    Effects of n-3 and n-6 fatty acids on the activities and expression of hepatic antioxidant enzymes in autoimmune-prone NZBxNZW F1 mice

    Lipids1 Aug 1994

More on CAT

Latest