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Klotho-derived peptide 1

Intervention

1 paper2 findings

PubChem

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1

Outcomes

2

KL

upin mice1

1 study

  1. Klotho-derived peptide 1 increases KL in mice.

    “which was associated with its restoration of Klotho expression at the posttranscriptional level.”

    Animalsin diseased kidneyskidney

    Klotho-derived peptide 1 inhibits cellular senescence in the fibrotic kidney by restoring Klotho expression via posttranscriptional regulation

    Theranostics1 Jan 2024

More on KL

Cellular senescence

downin mice1

1 study

  1. Klotho-derived peptide 1 inhibits cellular senescence in mice.

    “KP1 inhibited senescence markers p21, p16 and γ-H2AX in tubular epithelial cells of diseased kidneys”

    Animalsin tubular epithelial cells of diseased kidneyskidney

    Klotho-derived peptide 1 inhibits cellular senescence in the fibrotic kidney by restoring Klotho expression via posttranscriptional regulation

    Theranostics1 Jan 2024

More on Cellular senescence

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