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MIR223

Gene

3 papers1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals2
  • Cells1

Effects

1

KL

downin mice1

1 study

  1. MIR223 inhibits KL in mice.

    “Overexpression of miR-223-3p inhibited Klotho and induced p21, p16 and γ-H2AX, which were negated by KP1.”

    Animalsin mouse models of CKDkidney

    Klotho-derived peptide 1 inhibits cellular senescence in the fibrotic kidney by restoring Klotho expression via posttranscriptional regulation

    Theranostics1 Jan 2024

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