Interferon gamma
- 1 lab in 1 country
- 22 trials, 4 with no results posted
- Funders: Alvin J. Siteman Cancer Center and 8 more
- Animals1
Outcomes
1Clonal expansion
is required forin mice1
1 study
Clonal expansion
is required forin mice1
Interferon gamma is required for clonal expansion in mice.
“IFNγ-signaling is required for clonal expansion of Dnmt3a-mutant HSCs in vivo.”
Animalshematopoietic stress
Txnip Enhances Fitness of Dnmt3a-Mutant Hematopoietic Stem Cells via p21
Blood cancer discovery5 May 2022
Trial sponsors
Company1 trialPhase 1/278 people
Company1 trialPhase 137 people
Company1 trialPhase 123 people
1 trialPhase 3132 people
FDA Office of Orphan Products Development
1 trialPhase 330 people
Radboud University Medical Center
1 trialPhase 320 people
1 trialPhase 2/340 people
1 trialPhase 259 people
Funding
1 grant since 2023National Eye InstituteUS$374.9k
Latest
1 in 12 monthsJournal of Immunology Research
Tissue-Specific Expansion of Age-Associated B Cells via IFN-γ and IL-21 Within Salivary Glands in Sjögren Disease
Experiments in miceBlood and immune system