Intensive blood pressure control

Intervention2 papers2 findings

Human trial2

Outcomes

1

End-stage kidney disease

no changein humans1HR 1.05Low certainty

1 study

Intensive blood pressure control has no effect on end-stage kidney disease in humans (HR 1.05, 95% CI 0.74-1.48).
HumansSPRINT and ACCORD-BP participants
Effects of intensive blood pressure control on cardio-kidney outcomes by KDIGO risk categories: a Post Hoc analysis of ACCORD-BP and SPRINT trials · Hypertension research : official journal of the Japanese Society of Hypertension · 3 Sep 2026

End-stage kidney disease →

Associations

1

Myocardial infarction

downin humans1HR 0.68Low certainty

1 study

Intensive blood pressure control lowers the risk of myocardial infarction in humans (HR 0.68, 95% CI 0.59-0.78).
Humanscomposite adverse CV events in SPRINT and ACCORD-BP participants
Effects of intensive blood pressure control on cardio-kidney outcomes by KDIGO risk categories: a Post Hoc analysis of ACCORD-BP and SPRINT trials · Hypertension research : official journal of the Japanese Society of Hypertension · 3 Sep 2026

Myocardial infarction →

Latest

2

European Stroke JournalHuman trialYesterday

Intensive blood-pressure control for the prevention of major cardiovascular events in stroke patients: rationale and design of the OPTIMAL-STROKE trial

Cardiovascular disease

Hypertension ResearchHuman trial4 Sep

Effects of intensive blood pressure control on cardio-kidney outcomes by KDIGO risk categories: a Post Hoc analysis of ACCORD-BP and SPRINT trials