Incretins

  • 1 lab in 1 country
  • Funder: Università degli Studi di Pavia
  • 1 of 1 finding with company ties
  • Human trial1

Outcomes

1

Cognitive function

no changein humans1

1 study
  1. Incretins have no effect on cognitive function in humans.

    “Cognitive status did not change significantly during the 12 months of treatment in either group”

    Human trialtype 2 diabetes mellitus12 monthsn = 39

    12-month effects of incretins versus SGLT2-Inhibitors on cognitive performance and metabolic profile. A randomized clinical trial in the elderly with Type-2 diabetes mellitus

    Clinical pharmacology : advances and applications9 Oct 2018

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JCI Insight

Antibody reduced fat while preserving lean mass in mice

Experiments in middle-aged and aged mice found that an antibody targeting a stress-hormone signal reduced fat mass without reducing lean mass.Experiments in middle-aged and aged mice found that an antibody targeting a stress-hormone signal reduced fat mass without reducing lean mass.

Experiments in miceInterventions