Iatrogenic menopause

Intervention1 paper3 findings

Associations

3

Stroke

upin humans1

1 study

Iatrogenic menopause raises the risk of stroke in humans (PHR, 1.22; 95% CI, 1.15-1.28).
Reviewmedian follow-up 16.0 yearsfemalesn = 2,617,942
Age at Iatrogenic Menopause and Cardiovascular Morbidity and Mortality: A Systematic Review and Meta-Analysis · JAMA network open · 1 Oct 2026

Cardiovascular disease

upin humans1

1 study

Iatrogenic menopause raises the risk of cardiovascular disease in humans (PHR, 1.25; 95% CI, 1.12-1.39).
Reviewmedian follow-up 16.0 yearsfemalesn = 2,617,942
Age at Iatrogenic Menopause and Cardiovascular Morbidity and Mortality: A Systematic Review and Meta-Analysis · JAMA network open · 1 Oct 2026

Cardiovascular disease →

Mortality

upin humans1

1 study

Iatrogenic menopause raises the risk of mortality in humans (PHR, 1.08; 95% CI, 1.01-1.16).
Reviewmedian follow-up 16.0 yearsfemalesn = 2,617,942
Age at Iatrogenic Menopause and Cardiovascular Morbidity and Mortality: A Systematic Review and Meta-Analysis · JAMA network open · 1 Oct 2026

Latest

1

JAMA Network OpenReview2 Oct

Age at Iatrogenic Menopause and Cardiovascular Morbidity and Mortality: A Systematic Review and Meta-Analysis