Human trophoblast stem cell extracellular vesicles

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: National Cancer Institute and 3 more

Cells1

Outcomes

Inflammation

downin human cells1

1 study

Human trophoblast stem cell extracellular vesicles decrease inflammation in human cells.
“incubation of senescent cells with hTSC-EVs attenuated DNA damage and inflammatory signaling, at least in part by suppressing the function of NF-κB”
Cellssenescent cells; partly through suppression of NF-κB functionhuman fibroblast
The Secretome of Human Trophoblast Stem Cells Attenuates Senescence-Associated Traits
Aging cell12 Jan 2026

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Aging Cell12 Jan

The Secretome of Human Trophoblast Stem Cells Attenuates Senescence-Associated Traits

Experiments in human cellsInterventions

Paper

Human trophoblast stem cell extracellular vesicles

Outcomes

Latest

The Secretome of Human Trophoblast Stem Cells Attenuates Senescence-Associated Traits

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