Home-based cardiac rehabilitation

2 papers4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: National Institute on Aging

Human trial1
Humans1

Outcomes

4

Total cholesterol

downin humans1

1 study

Home-based cardiac rehabilitation decreases total cholesterol in humans.
“Serum total cholesterol (TC) continuously increased in the control group, whereas it decreased in the HBCR group at 12 months”
Human trialin patients with coronary artery disease12 monthsn = 259
Effectiveness of a comprehensive home-based cardiac rehabilitation intervention on the health promotion of patients with coronary artery disease: A randomized double-blind clinical trial
ARYA atherosclerosis1 Jan 2026

More on Total cholesterol

BMI

downin humans1

1 study

Home-based cardiac rehabilitation decreases BMI in humans.
“Body mass index (BMI) was significantly reduced in the HBCR group compared to the control group”
Human trialin patients with coronary artery diseasen = 259
Effectiveness of a comprehensive home-based cardiac rehabilitation intervention on the health promotion of patients with coronary artery disease: A randomized double-blind clinical trial
ARYA atherosclerosis1 Jan 2026

Return to work

upin humans1

1 study

Home-based cardiac rehabilitation improves return to work in humans.
“the rate of return to work after 6 months was significantly higher in the HBCR group”
Human trialin patients with coronary artery disease6 monthsn = 259
Effectiveness of a comprehensive home-based cardiac rehabilitation intervention on the health promotion of patients with coronary artery disease: A randomized double-blind clinical trial
ARYA atherosclerosis1 Jan 2026

Mortality

downin humans1

1 study

Home-based cardiac rehabilitation decreases mortality in humans.
“mortality was significantly higher in the control group after 18 months”
Human trialin patients with coronary artery disease18 monthsn = 259
Effectiveness of a comprehensive home-based cardiac rehabilitation intervention on the health promotion of patients with coronary artery disease: A randomized double-blind clinical trial
ARYA atherosclerosis1 Jan 2026

Funding

1 grant since 2023

National Institute on AgingUS$2m

Home-based cardiac rehabilitation using a novel mobile health exercise regimen following transcatheter heart valve interventions (HOME RUN HITTER)
National Institute on AgingVanderbilt University Medical CenterUS$564.1k2022–2027

Latest

2 in 12 months

ARYA Atherosclerosis26 Aug

Effectiveness of a comprehensive home-based cardiac rehabilitation intervention on the health promotion of patients with coronary artery disease: A randomized double-blind clinical trial

Randomised trial in 259 peopleCoronary artery disease

AHA Scientific Sessions 2025 Abstract3 Nov

Exercise Dose During Home-Based Cardiac Rehabilitation and Mortality

Cohort study of 855 peoplePopulations