AgingResearch.NewsJoin free

Glrx3+ extracellular vesicle-loaded hydrogel

Intervention

1 paper studies it3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Guangzhou Science and Technology Program key projects and 3 more
  • Animals1

Outcomes

3

Extracellular matrix remodeling

upin rats1

1 study

  1. Glrx3+ extracellular vesicle-loaded hydrogel improves extracellular matrix remodeling in rats.

    “restored ECM deposition by modulating the redox homeostasis”

    Animalsin a rat model of disc degeneration

    A Redox Homeostasis Modulatory Hydrogel with GLRX3⁺ Extracellular Vesicles Attenuates Disc Degeneration by Suppressing Nucleus Pulposus Cell Senescence

    ACS nanoJul 11, 2023

More on Extracellular matrix remodeling

Cellular senescence

downin rats1

1 study

  1. Glrx3+ extracellular vesicle-loaded hydrogel inhibits cellular senescence in rats.

    “alleviated the NP senescence state”

    Animalsin a rat model of disc degeneration

    A Redox Homeostasis Modulatory Hydrogel with GLRX3⁺ Extracellular Vesicles Attenuates Disc Degeneration by Suppressing Nucleus Pulposus Cell Senescence

    ACS nanoJul 11, 2023

More on Cellular senescence

Mitochondrial damage

downin rats1

1 study

  1. Glrx3+ extracellular vesicle-loaded hydrogel decreases mitochondrial damage in rats.

    “EVs-GLRX3-loaded hydrogel attenuated mitochondrial damage”

    Animalsin a rat model of disc degeneration

    A Redox Homeostasis Modulatory Hydrogel with GLRX3⁺ Extracellular Vesicles Attenuates Disc Degeneration by Suppressing Nucleus Pulposus Cell Senescence

    ACS nanoJul 11, 2023

Latest

Related