Autophagy
upin worms1
Ginsenoside RG3 increases autophagy in worms.
“Rg3 restored age-impaired lysosomal function and autophagic flux in neurons.”
Model organismsneuron
Ginseng compound extended lifespan and preserved movement in worms
Aging cell1 Oct 2026
Neurodegeneration
downin worms1
Ginsenoside RG3 protects against neurodegeneration in worms.
“protected dopaminergic neurons against α-synuclein-induced degeneration.”
Model organismsα-synuclein expressiondopaminergic neurons
Ginseng compound extended lifespan and preserved movement in worms
Aging cell1 Oct 2026
Protein aggregates
downin worms1
Ginsenoside RG3 decreases protein aggregates in worms.
“suppressed neuronal polyglutamine aggregation, and protected dopaminergic neurons against α-synuclein-induced degeneration.”
Model organismspolyglutamine expressionneuron
Ginseng compound extended lifespan and preserved movement in worms
Aging cell1 Oct 2026
Locomotion
upin worms1
Ginsenoside RG3 improves locomotion in worms.
“Rg3 extended lifespan and preserved key physiological outputs, including locomotion and pharyngeal pumping”
Model organisms
Ginseng compound extended lifespan and preserved movement in worms
Aging cell1 Oct 2026
Lifespan
upin worms1
Ginsenoside RG3 extends lifespan in worms.
“Rg3 extended lifespan and preserved key physiological outputs, including locomotion and pharyngeal pumping, indicating that Rg3 delays functional aging.”
Model organisms
Ginseng compound extended lifespan and preserved movement in worms
Aging cell1 Oct 2026
In worm experiments, the ginseng-derived compound also preserved touch sensitivity and restored age-impaired function in nerve cells’ waste-processing compartments.In worm experiments, the ginseng-derived compound also preserved touch sensitivity and restored age-impaired function in nerve cells’ waste-processing compartments.