AgingResearch.NewsJoin free

Germ-free state

Exposure

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Exploratory Research for Advanced Technology and 7 more
  • Animals1

Outcomes

2

Extracellular matrix remodelling

downin mice1

1 study

  1. Germ-free state decreases extracellular matrix remodelling in mice.

    “In particular, the gene sets associated with inflammatory signatures (i.e., inflammation and tissue remodeling) were found to be suppressed in female GF mice.”

    Animalsaged germ-free vs SPFliverfemales

    Transcriptomic and lipidomic analysis of aging-associated inflammatory signature in mouse liver

    Inflammation and regeneration3 May 2025

More on Extracellular matrix remodelling

Inflammation

downin mice1

1 study

  1. Germ-free state decreases inflammation in mice.

    “In particular, the gene sets associated with inflammatory signatures (i.e., inflammation and tissue remodeling) were found to be suppressed in female GF mice.”

    Animalsaged germ-free vs SPFliverfemales

    Transcriptomic and lipidomic analysis of aging-associated inflammatory signature in mouse liver

    Inflammation and regeneration3 May 2025

More on Inflammation

Latest

Related