Gemcitabine
- Human trial1
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4 in 12 monthsCancer Discovery
Senescent Cancer-Associated Fibroblasts Drive Early-Stage Lymph Node Metastasis in Pancreatic Cancer through Lactate-Mediated Metabolic-Epigenetic Rewiring
Non-randomised trial in peoplePancreatic cancer
Journal of Medicinal Chemistry
Design and Optimization of Lysosome-Targeted β-Galactoside Senolytic Prodrugs: Harnessing the Aromatic Ring of Self-Immolative Linkers
Experiments in miceInterventions
Cancer Letters
Vitamin B3 derivatives support pancreatic cancer cell survival and chemotherapy resistance
Experiments in animalsInterventions
Biochemical Pharmacology
Nicotinamide riboside enhances the efficacy of gemcitabine and suppresses PDAC premalignant lesions via SIRT3 activation
Experiments in animalsInterventions