Gamma radiation

Exposure

3 papers3 findings

  • 2 independent labs in 1 country
  • Funders: National Cancer Institute and 4 more
  • Humans1
  • Cells1

Outcomes

2

Chronic lymphocytic leukemia

no changein humans1

1 study
  1. Gamma radiation has no effect on chronic lymphocytic leukemia in humans.

    “There was no evidence of external exposure effects on the risks of death from chronic lymphocytic leukemia, lymphoma, or multiple myeloma.”

    Humansexternal gamma ray exposure

    Leukemia, Lymphoma, and Multiple Myeloma Mortality in the Russian Mayak Worker Cohort 1948-2015

    Radiation research23 Oct 2025

More on Chronic lymphocytic leukemia

CDKN1A

upin human cells1

1 study
  1. Gamma radiation induces CDKN1A in human cells.

    “Gamma irradiation, DNA-damaging drugs, expression of p14(ARF) or oncogenic Ras, and replicative exhaustion all resulted in elevated EYFP expression”

    Cellsfibroblast

    Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence

    Aging cell1 Dec 2003

More on CDKN1A

Associations

1

non-CLL leukemia

upin humans1

1 study
  1. Gamma radiation raises the risk of non-CLL leukemia in humans (ERR 2.45 at 1 Gy (95% CI 0.33 to 11.9)).

    “While the largest ERRs [2.45 at 1 Gy, 95% confidence interval (CI) 0.33 to 11.9] were associated with external doses received between 2 and 5 years before death”

    Humansprotracted external low-dose-rate gamma ray exposurered bone marrow

    Leukemia, Lymphoma, and Multiple Myeloma Mortality in the Russian Mayak Worker Cohort 1948-2015

    Radiation research23 Oct 2025

More on non-CLL leukemia

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