Foretinib

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: National Research Foundation and 1 more

Animals1

Outcomes

Bone loss

downin mice1

1 study

Foretinib protects against bone loss in mice.
“In ovariectomized, estrogen-deficient mice, foretinib significantly reduced trabecular and cortical bone loss by enhancing in vivo osteoblast differentiation”
Animalsovariectomized, estrogen-deficient micefemur
Foretinib Alleviates Osteoblast Senescence and Protects Against Bone Loss in Ovariectomized Mice by Promoting Osteoblast Differentiation
Cells8 Dec 2025

Stem cell differentiation

upin mouse cells1

1 study

Foretinib improves stem cell differentiation in mouse cells.
“foretinib restored the impaired osteogenic differentiation of aged osteoblasts to near-normal levels in vitro”
Cellsin aged osteoblasts
Foretinib Alleviates Osteoblast Senescence and Protects Against Bone Loss in Ovariectomized Mice by Promoting Osteoblast Differentiation
Cells8 Dec 2025

Latest

1 in 12 months

Cells24 Dec

Foretinib Alleviates Osteoblast Senescence and Protects Against Bone Loss in Ovariectomized Mice by Promoting Osteoblast Differentiation

Experiments in miceBones and joints

Paper

Foretinib

Outcomes

Latest

Foretinib Alleviates Osteoblast Senescence and Protects Against Bone Loss in Ovariectomized Mice by Promoting Osteoblast Differentiation

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