Fluoroalkylated polypyridinium
1 paper5 findings
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 1 more
- Animals1
Outcomes
4Mitophagy
upin animals1upin cells1
1 study
Mitophagy
upin animals1upin cells1
Fluoroalkylated polypyridinium induces mitophagy.
“After intravenous administration, the nanoparticle reduces oxidative stress, promotes mitophagy, and decreases cellular senescence in atherosclerotic plaques”
Animalsin atherosclerotic plaquesatherosclerotic plaque
Nature communications7 Nov 2025
Fluoroalkylated polypyridinium activates mitophagy in cells.
“The polymer effectively restores mitochondrial function and alleviates the inflammatory response in foam cells by activating mitophagy”
Cellsin foam cells
Nature communications7 Nov 2025
Cellular senescence
downin animals1
1 study
Cellular senescence
downin animals1
Fluoroalkylated polypyridinium decreases cellular senescence.
“reduces oxidative stress, promotes mitophagy, and decreases cellular senescence in atherosclerotic plaques, contributing to high therapeutic efficacy”
Animalsin atherosclerotic plaquesatherosclerotic plaque
Nature communications7 Nov 2025
Oxidative stress and ROS signalling
downin animals1
1 study
Oxidative stress and ROS signalling
downin animals1
Fluoroalkylated polypyridinium decreases oxidative stress and ROS signalling.
“the nanoparticle reduces oxidative stress, promotes mitophagy, and decreases cellular senescence in atherosclerotic plaques”
Animalsin atherosclerotic plaquesatherosclerotic plaque
Nature communications7 Nov 2025
Inflammation
downin cells1
1 study
Inflammation
downin cells1
Fluoroalkylated polypyridinium decreases inflammation in cells.
“alleviates the inflammatory response in foam cells by activating mitophagy”
Cellsin foam cells
Nature communications7 Nov 2025