Tirzepatide + testosterone + exercise

Intervention

1 paper4 findings

  • 1 lab
  • 4 of 4 findings with company ties
  • Human trial1

Outcomes

4

HbA1c

downin humans1

1 study
  1. Tirzepatide + testosterone + exercise decreases HbA1c in humans (from 10.1% to 5.8%).

    “HbA1c decreased from 10.1% to 5.8%”

    Humansin patients with type 2 diabetes12 monthsmalesn = 45

    Increasing skeletal muscle mass and strength during incretin-based weight loss

    Obesity pillars10 Aug 2026

More on HbA1c

Body weight

downin humans1

1 study
  1. Tirzepatide + testosterone + exercise decreases body weight in humans (-20.9-22.6 kg (18-20%)).

    “body weight decreased by 20.9-22.6 kg (18-20%)”

    Humans12 monthsmalesn = 93

    Increasing skeletal muscle mass and strength during incretin-based weight loss

    Obesity pillars10 Aug 2026

Grip strength

upin humans1

1 study
  1. Tirzepatide + testosterone + exercise improves grip strength in humans (+5.7-7.1 kg (18-21%)).

    “grip strength increased by 5.7-7.1 kg (18-21%)”

    Humans12 monthsmalesn = 93

    Increasing skeletal muscle mass and strength during incretin-based weight loss

    Obesity pillars10 Aug 2026

More on Grip strength

Skeletal muscle mass

upin humans1

1 study
  1. Tirzepatide + testosterone + exercise increases skeletal muscle mass in humans (+1.6-3.7 kg (4-12%)).

    “SMM increased by 1.6-3.7 kg (4-12%)”

    Humans12 monthsmalesn = 93

    Increasing skeletal muscle mass and strength during incretin-based weight loss

    Obesity pillars10 Aug 2026

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