Engineered exosomes delivering NLRX1K520R
Intervention1 paper1 finding
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
Funders: National Natural Science Foundation of China and 3 more
- Animals1
Outcomes
1Intervertebral disc degeneration
downin mice1
1 study
Intervertebral disc degeneration
downin mice1
Engineered exosomes delivering NLRX1K520R decreases intervertebral disc degeneration in mice.
Animals
Ubiquitination-mediated degradation of NLRX1 drives metabolic vulnerability and accelerates intervertebral disc degeneration · Cell death and differentiation · 23 Sep 2026