NLRX1
Gene2 papers2 findingsHGNC 29890NCBI Gene 79671Taxon 9606
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
A gene’s or a process’s line counts the gene with the processes named after it, as NLRP3 with the NLRP3 inflammasome, and the trials of drugs aimed at it.
Funders: National Natural Science Foundation of China and 4 more
- Animals2
Effects
2Oxidative phosphorylation
upin mouse cells1
1 study
Oxidative phosphorylation
upin mouse cells1
NLRX1 improves oxidative phosphorylation in mouse cells.
Cellssenescence-inducing conditions
Ubiquitination-mediated degradation of NLRX1 drives metabolic vulnerability and accelerates intervertebral disc degeneration · Cell death and differentiation · 23 Sep 2026
Intervertebral disc degeneration
downin mice1
1 study
Intervertebral disc degeneration
downin mice1
NLRX1 protects against intervertebral disc degeneration in mice.
Animalsshown by knockout
Ubiquitination-mediated degradation of NLRX1 drives metabolic vulnerability and accelerates intervertebral disc degeneration · Cell death and differentiation · 23 Sep 2026
Funding
National Institute on AgingUS$351.8k1 grant since 2024