Empagliflozin + exercise
1 paper4 findings
- 1 lab in 1 country
- Funders: Boehringer Ingelheim and 1 more
- 4 of 4 findings with company ties
- Animals1
Outcomes
4Autophagy
upin rats1
1 study
Autophagy
upin rats1
Empagliflozin + exercise activates autophagy in rats.
“Combination treatment significantly enhanced citrate synthase activity, mitochondrial functional protein expression, and autophagic flux.”
Animalsspontaneously diabetic Torii fatty ratssoleus8 weeksmales
The journal of physiological sciences : JPS7 Jul 2026
Citrate synthase activity
upin rats1
1 study
Citrate synthase activity
upin rats1
Empagliflozin + exercise increases citrate synthase activity in rats.
“Combination treatment significantly enhanced citrate synthase activity, mitochondrial functional protein expression, and autophagic flux.”
Animalsspontaneously diabetic Torii fatty ratssoleus8 weeksmales
The journal of physiological sciences : JPS7 Jul 2026
Triglyceride
downin rats1
1 study
Triglyceride
downin rats1
Empagliflozin + exercise decreases triglyceride in rats.
“Additionally, the combined treatment reduced total cholesterol and triglycerides compared with EMPA alone.”
Animalsspontaneously diabetic Torii fatty rats, compared with EMPA alone8 weeksmales
The journal of physiological sciences : JPS7 Jul 2026
Total cholesterol
downin rats1
1 study
Total cholesterol
downin rats1
Empagliflozin + exercise decreases total cholesterol in rats.
“Additionally, the combined treatment reduced total cholesterol and triglycerides compared with EMPA alone.”
Animalsspontaneously diabetic Torii fatty rats, compared with EMPA alone8 weeksmales
The journal of physiological sciences : JPS7 Jul 2026