Differentiation protocol

Exposure

1 paper3 findings

  • 1 lab in 1 country
  • Funders: Chinese Academy of Sciences and 1 more
  • Cells1

Outcomes

3

Mitochondrion

downin human cells1

1 study
  1. Differentiation protocol impairs mitochondrion in human cells.

    “Despite reduced mitochondrial health in iMSC3 and iMSC4 (P ≤ 0.001)”

    Cellsin iMSC3 and iMSC4

    Impact of differentiation protocols on the functionality of mesenchymal stem cells derived from induced pluripotent stem cells

    World journal of stem cells26 Dec 2025

Osteogenic differentiation

upin human cells1

1 study
  1. Differentiation protocol increases osteogenic differentiation in human cells.

    “EB-iMSC and iMSC2 showed enhanced osteogenesis (runt-related transcription factor 2; P ≤ 0.01 and P ≤ 0.0001, respectively)”

    Cellsin EB-iMSC and iMSC2 relative to MSCs

    Impact of differentiation protocols on the functionality of mesenchymal stem cells derived from induced pluripotent stem cells

    World journal of stem cells26 Dec 2025

Reactive oxygen species

downin human cells1

1 study
  1. Differentiation protocol decreases reactive oxygen species in human cells.

    “reactive oxygen species levels were lower in all iMSCs (P values ranged from 0.001 to 0.0001)”

    Cellsrelative to primary bone marrow MSCs

    Impact of differentiation protocols on the functionality of mesenchymal stem cells derived from induced pluripotent stem cells

    World journal of stem cells26 Dec 2025

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