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Deuterium-depleted water

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: European Commission and 1 more
  • Animals1

Outcomes

3

Mitochondrion

upin mouse cells1

1 study

  1. Deuterium-depleted water improves mitochondrion in mouse cells.

    “incubation of primary neuronal cultures in DDW-containing buffer ameliorated Ca2+ influx and mitochondrial potential in a toxicity model”

    Cellstoxicity model

    Transcriptomic Insights into Late-Life Depression and the Role of Environmental Drinking Water Composition: A Study on 18-Month-Old Mice

    International journal of molecular sciences31 Oct 2025

Memory

upin mice1

1 study

  1. Deuterium-depleted water improves memory in mice.

    “Housing on DDW increased their hedonic sensitivity and novelty exploration, reduced helplessness, improved memory”

    Animals~90 ppmbrain21 days

    Transcriptomic Insights into Late-Life Depression and the Role of Environmental Drinking Water Composition: A Study on 18-Month-Old Mice

    International journal of molecular sciences31 Oct 2025

Late-life depression

downin mice1

1 study

  1. Deuterium-depleted water decreases late-life depression in mice.

    “Housing on DDW increased their hedonic sensitivity and novelty exploration, reduced helplessness, improved memory”

    Animals~90 ppmbrain21 days

    Transcriptomic Insights into Late-Life Depression and the Role of Environmental Drinking Water Composition: A Study on 18-Month-Old Mice

    International journal of molecular sciences31 Oct 2025

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