Conjugated bile acids

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: National Major Science and Technology Projects of China and 1 more
  • Animals1

Outcomes

1

Mitochondrial damage

upin mice1

1 study
  1. Conjugated bile acids increase mitochondrial damage in mice.

    “In cholangiocytes, substantial accumulation of conjugated primary bile acids significantly induced mitochondrial damage through the opening of the mitochondrial permeability transition pore”

    Animalscholangiocytes

    Conjugated bile acids facilitate cholangiocyte senescence to promote cholestatic liver diseases via STING signaling

    Journal of advanced research12 Mar 2026

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