Conjugated bile acids
1 paper1 finding
- 1 lab in 1 country
- Funders: National Major Science and Technology Projects of China and 1 more
- Animals1
Outcomes
1Mitochondrial damage
upin mice1
1 study
Mitochondrial damage
upin mice1
Conjugated bile acids increase mitochondrial damage in mice.
“In cholangiocytes, substantial accumulation of conjugated primary bile acids significantly induced mitochondrial damage through the opening of the mitochondrial permeability transition pore”
Animalscholangiocytes
Journal of advanced research12 Mar 2026
Latest
1 in 12 monthsJournal of Advanced Research
Conjugated bile acids facilitate cholangiocyte senescence to promote cholestatic liver diseases via STING signaling
Experiments in micecGAS–STING signalling