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Comp. 1

Intervention

1 paper studies it3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1

Outcomes

3

extracellular-matrix

upin cells1

1 study

  1. Comp. 1 increases extracellular-matrix in cells.

    “increases the expression of extracellular matrix proteins COL-2 and aggrecan”

    Cellsin vitro

    Sequential Targeted Enzyme-Instructed Self-Assembly Supramolecular Nanofibers to Attenuate Intervertebral Disc Degeneration

    Advanced materials (Deerfield Beach, Fla.)Sep 2, 2024

DNA damage response

downin cells1

1 study

  1. Comp. 1 decreases DNA damage response in cells.

    “Additionally, it can reduce the expression of Senescence-Associated Secretory Phenotype and DNA damage in aged nucleus pulposus cells”

    Cellsin vitro in aged nucleus pulposus cells

    Sequential Targeted Enzyme-Instructed Self-Assembly Supramolecular Nanofibers to Attenuate Intervertebral Disc Degeneration

    Advanced materials (Deerfield Beach, Fla.)Sep 2, 2024

More on DNA damage response

Senescence-associated secretory phenotype (SASP)

downin cells1

1 study

  1. Comp. 1 decreases senescence-associated secretory phenotype (SASP) in cells.

    “Additionally, it can reduce the expression of Senescence-Associated Secretory Phenotype and DNA damage in aged nucleus pulposus cells”

    Cellsin vitro in aged nucleus pulposus cells

    Sequential Targeted Enzyme-Instructed Self-Assembly Supramolecular Nanofibers to Attenuate Intervertebral Disc Degeneration

    Advanced materials (Deerfield Beach, Fla.)Sep 2, 2024

More on Senescence-associated secretory phenotype (SASP)

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