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Colostrinin

Intervention

2 papers7 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: National Institute of Environmental Health Sciences and 2 more
  • 3 of 3 findings with company ties
  • Cells1

Outcomes

6

Cognitive function

upin humans2

2 studies

  1. Colostrinin improves cognitive function in humans.

    “has been shown to have a stabilizing effect on cognitive function in Alzheimer's disease patients”

    Reviewin Alzheimer's disease patients

    Colostrinin: an oxidative stress modulator for prevention and treatment of age-related disorders

    Journal of Alzheimer's disease : JAD1 Apr 2008

  2. Colostrinin improves cognitive function in humans.

    “its administration to patients with Alzheimer's disease resulted in improved cognitive functions.”

    Reviewpatients with Alzheimer's disease

    Colostrinin delays the onset of proliferative senescence of diploid murine fibroblast cells

    Neuropeptides1 Apr 2007

Motor and sensory activities

upin mice1

1 study

  1. Colostrinin improves motor and sensory activities in mice.

    “CLN increased the lifespan and improved various motor and sensory activities.”

    Revieworal

    Colostrinin: an oxidative stress modulator for prevention and treatment of age-related disorders

    Journal of Alzheimer's disease : JAD1 Apr 2008

Lifespan

upin mice1

1 study

  1. Colostrinin extends lifespan in mice.

    “When given orally to mice, CLN increased the lifespan and improved various motor and sensory activities.”

    Revieworal

    Colostrinin: an oxidative stress modulator for prevention and treatment of age-related disorders

    Journal of Alzheimer's disease : JAD1 Apr 2008

Reactive oxygen species

downin mouse cells1

1 study

  1. Colostrinin decreases reactive oxygen species in mouse cells.

    “This action of CLN is associated with a decrease in the intracellular levels of reactive oxygen species”

    Cellscultured MDF

    Colostrinin delays the onset of proliferative senescence of diploid murine fibroblast cells

    Neuropeptides1 Apr 2007

More on Reactive oxygen species

Population doublings

upin mouse cells1

1 study

  1. Colostrinin increases population doublings in mouse cells.

    “increases their population doubling levels.”

    Cellscultured MDF

    Colostrinin delays the onset of proliferative senescence of diploid murine fibroblast cells

    Neuropeptides1 Apr 2007

More on Population doublings

Cellular senescence

downin mouse cells1

1 study

  1. Colostrinin decreases cellular senescence in mouse cells.

    “CLN significantly decelerates the senescence of cultured MDF and increases their population doubling levels.”

    Cellscultured MDF

    Colostrinin delays the onset of proliferative senescence of diploid murine fibroblast cells

    Neuropeptides1 Apr 2007

More on Cellular senescence

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