Cognitive activity

Intervention1 paper2 findings

  • Humans1

Associations

1

Alzheimer's disease

no changein humans1downin humans1OR 0.66–0.91Low certainty

1 study

  1. Cognitive activity is associated with Alzheimer's disease in humans (OR 0.91, 95% CI 0.71–1.18).

    Humansreading, storytelling, and playing games

    Midlife and late-life cognitive activity tied to lower dementia risk · Neurology open access · 10 Jan 2025

  2. Cognitive activity lowers the risk of Alzheimer's disease in humans (OR 0.66, 95% CI 0.51–0.87).

    Humansoccupational cognitive activity and complexity

    Midlife and late-life cognitive activity tied to lower dementia risk · Neurology open access · 10 Jan 2025

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Neurology Open AccessHumans

Midlife and late-life cognitive activity tied to lower dementia risk

Per standard-deviation increase, odds ratios for Alzheimer's disease dementia were 0.66 for midlife and 0.50 for late-life cognitive activity, but…Per standard-deviation increase, odds ratios for Alzheimer's disease dementia were 0.66 for midlife and 0.50 for late-life cognitive activity, but 0.91 for childhood activity.

Alzheimer's disease

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