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Circular RNA encoding human telomerase

Circular RNA encoding human telomerase has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Nov 9, 2026: “Vessel lining cells show more damage in progeria mice”.

Intervention

1 paper studies it4 findingsUpdated

1 new paper in 30 daysSee all 1 papers on circular RNA encoding human telomerase

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

What did studies of circular RNA encoding human telomerase find?

4

Studies of circular RNA encoding human telomerase measured 4 outcomes, among them lifespan, tissue fibrosis and endothelial inflammatory activation.

Lifespan

upin mice1

1 study

  1. Circular RNA encoding human telomerase extends lifespan in mice (HGPS mice).

    “restoration of endothelial function using circular RNA telomerase is associated with improved hepatic and renal function and increased life span.”

    AnimalsHGPS micecircular RNA

    Vessel lining cells show more damage in progeria mice

    AHA Scientific Sessions 2026 abstract

Tissue fibrosis

downin mice1

1 study

  1. Circular RNA encoding human telomerase decreases tissue fibrosis in mice (HGPS mice).

    “decreased tissue fibrosis and immune infiltration, and improved systemic physiological parameters in HGPS mice.”

    AnimalsHGPS micecircular RNA

    Vessel lining cells show more damage in progeria mice

    AHA Scientific Sessions 2026 abstract

Endothelial inflammatory activation

downin mice1

1 study

  1. Circular RNA encoding human telomerase decreases endothelial inflammatory activation in mice (HGPS mice).

    “systemic circRNA TERT delivery reduced endothelial inflammatory activation and senescence in liver and kidney microvasculature”

    AnimalsHGPS micecircular RNAliver and kidney microvasculature

    Vessel lining cells show more damage in progeria mice

    AHA Scientific Sessions 2026 abstract

Cellular senescence

downin mice1

1 study

  1. Circular RNA encoding human telomerase decreases cellular senescence in mice (HGPS mice).

    “systemic circRNA TERT delivery reduced endothelial inflammatory activation and senescence in liver and kidney microvasculature”

    AnimalsHGPS micecircular RNAliver and kidney microvasculature

    Vessel lining cells show more damage in progeria mice

    AHA Scientific Sessions 2026 abstract

More on Cellular senescence

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months
AHA Scientific Sessions 2026 Abstract

Vessel lining cells show more damage in progeria mice

Restoring vessel-lining function was linked to better liver and kidney function and longer lifespan in mice modeling the premature-aging disorder.Restoring vessel-lining function was linked to better liver and kidney function and longer lifespan in mice modeling the premature-aging disorder.

Mouse studyProgeria
Paper

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