AHA Scientific Sessions 2026 Abstract
Vessel lining cells show more damage in progeria mice
Restoring vessel-lining function was linked to better liver and kidney function and longer lifespan in mice modeling the premature-aging disorder.Restoring vessel-lining function was linked to better liver and kidney function and longer lifespan in mice modeling the premature-aging disorder.
Mouse studyProgeria
Who was studiedHGPS mice, against VSMCs
What changedDNA damage, telomere erosion, and senescence markers were more pronounced in vessel lining cells than in vessel muscle cells
The catchThe conference abstract gives no mouse group sizes, treatment dose, or lifespan effect size