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Cilostazol

Intervention

2 papers study it4 more mention it2 findings

PubChemChEBIMeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

About aging: trials about aging, of every trial that tests the drug for any use.

  • 2 independent labs in 2 countries
  • 2 trials, none about aging
  • Funder: National Institute for Health and Care Research
  • Animals2

Outcomes

2

Inflammation

downin mice1

1 study

  1. Cilostazol decreases inflammation in mice.

    “Cilostazol as a new STING inhibitor that attenuates aging-related endothelial inflammation both in vitro and in vivo”

    Animalsaging-related

    Cytosolic DNA initiates a vicious circle of aging-related endothelial inflammation and mitochondrial dysfunction via STING: the inhibitory effect of Cilostazol

    Acta pharmacologica SinicaApr 30, 2024

More on Inflammation

Vasodilation

upin rats1

1 study

  1. Cilostazol improves vasodilation in rats.

    “pretreatment of aortas with cilostazol enhanced the potency of atorvastatin in both young and adult aortas.”

    Animalsprecontracted with phenylephrinethoracic aorta rings10−6 Mfemales

    Cilostazol enhances atorvastatin-induced vasodilation of female rat aorta during aging

    Physiology internationalSep 1, 2017

Trial sponsors

Funding

1 grant since 2025

National Institute for Health and Care Research£2.7m

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