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Cell membrane-coated keratin nanoparticles

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

2

Extracellular matrix remodelling

upin cells1

1 study

  1. Cell membrane-coated keratin nanoparticles improve extracellular matrix remodelling in cells.

    “In addition, MKNs activate integrins at the cell membrane and enhance the interactions between NP cells and ECM, resulting in increased ECM anabolism and decreased catabolism.”

    Cellsnucleus pulposus

    Engineered Cell Membrane-Coated Keratin Nanoparticles Attenuated Intervertebral Disc Degeneration by Remodeling the Disc Microenvironment

    Advanced healthcare materials28 Jan 2025

More on Extracellular matrix remodelling

Cellular senescence

downin cells1

1 study

  1. Cell membrane-coated keratin nanoparticles decrease cellular senescence in cells.

    “Moreover, MKNs modulate mitochondrial metabolism and attenuate NP cell senescence.”

    Cellsnucleus pulposus

    Engineered Cell Membrane-Coated Keratin Nanoparticles Attenuated Intervertebral Disc Degeneration by Remodeling the Disc Microenvironment

    Advanced healthcare materials28 Jan 2025

More on Cellular senescence

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