Capsaicin

3 papers2 findings

PubChem ChEBI MeSH

1 lab in 1 country

Animals1

Outcomes

2

Coronary relaxation

upin mice1

1 study

Capsaicin improves coronary relaxation in mice.
“In vivo, dietary capsaicin supplementation enhanced coronary relaxation and prolonged the survival duration of HFD-fed ApoE(-/-) mice.”
Animalsin HFD-fed ApoE(-/-) micedietary capsaicin supplementation0.01%
Ameliorating Endothelial Mitochondrial Dysfunction Restores Coronary Function via Transient Receptor Potential Vanilloid 1-Mediated Protein Kinase A/Uncoupling Protein 2 Pathway
Hypertension (Dallas, Tex. : 1979)14 Dec 2015

Lifespan

upin mice1

1 study

Capsaicin extends lifespan in mice.
“dietary capsaicin supplementation enhanced coronary relaxation and prolonged the survival duration of HFD-fed ApoE(-/-) mice.”
Animalsin HFD-fed ApoE(-/-) micedietary capsaicin supplementation0.01%
Ameliorating Endothelial Mitochondrial Dysfunction Restores Coronary Function via Transient Receptor Potential Vanilloid 1-Mediated Protein Kinase A/Uncoupling Protein 2 Pathway
Hypertension (Dallas, Tex. : 1979)14 Dec 2015

Latest

2 in 12 months

Journal of Cellular and Molecular Medicine25 Apr

Capsaicin Receptor TRPV1 Delays Aortic Aging in Atherosclerotic Mice by Inhibiting the ISG15-p53 Pathway

Experiments in miceMechanisms

Journal of the Peripheral Nervous System7 Jan

Evaluation of Nicotinamide Riboside in Prevention of Small Nerve Fiber Axon Degeneration and Promotion of Nerve Regeneration

Randomised trial in peopleNicotinamide riboside

Food & Function11 Jul

Non-pungent capsiate enhances longevity and healthspan in Caenorhabditis elegans via transient receptor potential (TRP) channels

Experiments in wormsInterventions

Experimental Cell Research16 Jun

Medication targeting to subcellular organelles: Emphasizing mitochondria as a therapeutic marvel-Current situation and future prospects

ReviewInterventions

Aging and Disease18 Feb

Capsaicin and TRPV1: A Novel Therapeutic Approach to Mitigate Vascular Aging

ReviewInterventions

Journal of Medicinal Chemistry17 Jan

Discovery of (3-Phenylcarbamoyl-3,4-dihydro-2H-pyrrol-2-yl)phosphonates as Imidazoline I₂ Receptor Ligands with Anti-Alzheimer and Analgesic Properties

Experiments in animalsInterventions

Physiology & Behavior4 Nov

Taste and oral somatosensation: Role of PTC bitter sensitivity, gender, and age

Study in peoplePopulations

Genes to Cells13 Sep

Capsaicin modulates TRPV1, induces β-defensin expression, and regulates NF-κB in oral senescent cells and a murine model

Experiments in animalsInterventions

Experimental Gerontology29 Oct

Age-dependent down-regulation of orexin receptors in trigeminal nucleus caudalis correlated with attenuation of orexinergic analgesia in rats

Experiments in animalsMechanisms

Cytokine6 Jul

Aging exaggerates pulpal pain sensation by increasing the expression levels of nociceptive neuropeptides and inflammatory cytokines

Experiments in animalsMechanisms