Candida

1 paper2 findings

1 lab in 1 country

Funders: Case Western Reserve University and 4 more

Humans1

Outcomes

1

Dysfunctional regulatory T cells

upin human cells1

1 study

Candida induces dysfunctional regulatory T cells in human cells.
“Candida can induce both proliferation and dysfunction of Tregs in an IL-6 dependent manner”
Cellsin vitro, IL-6 dependent
Enrichment of Candida associated with dysbiosis contributes to mucosal CD4⁺FOXP3⁺ regulatory T cell accrual and their dysfunction in aging
Frontiers in immunology19 Mar 2026

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Associations

1

Dysfunctional regulatory T cells

upin humans1

1 study

Candida is associated with dysfunctional regulatory T cells in humans.
“abundance of Candida is positively correlated with elevated levels of mucosal Tregs, dysfunctional Tregs (TregDys), and hyperactivated CD4+ T cells.”
Humansoral mucosa
Enrichment of Candida associated with dysbiosis contributes to mucosal CD4⁺FOXP3⁺ regulatory T cell accrual and their dysfunction in aging
Frontiers in immunology19 Mar 2026

More on Dysfunctional regulatory T cells

Funding

1 grant since 2020

Japan Society for the Promotion of ScienceJP¥4.4m

Development of a new preventive method for aspiration pneumonia based on property analysis of Candida bacteria collected from different oral environments
Japan Society for the Promotion of ScienceKagoshima UniversityJP¥4.4m2020–2023

Latest

1 in 12 months

Frontiers in Immunology6 Apr

Enrichment of Candida associated with dysbiosis contributes to mucosal CD4⁺FOXP3⁺ regulatory T cell accrual and their dysfunction in aging

Cohort study in peopleMicrobiome composition