AgingResearch.NewsJoin free

Butylphthalide

Intervention

1 paper3 findings

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Cells1

Outcomes

3

SASP-related gene expression

downin human cells1

1 study

  1. Butylphthalide decreases SASP-related gene expression in human cells.

    “Moreover, NBP was shown to suppress the expression of SASP-related genes.”

    CellsAβ oligomer exposureU87

    3-N-Butylphthalide alleviate Aβ-induced cellular senescence through the CDK2-pRB1-Caspase3 axis

    Brain research28 Dec 2024

More on SASP-related gene expression

Apoptosis

downin human cells1

1 study

  1. Butylphthalide decreases apoptosis in human cells.

    “we demonstrate that NBP ameliorate Aβ oligomer-induced cellular senescence and apoptosis”

    CellsAβ oligomer exposureU87

    3-N-Butylphthalide alleviate Aβ-induced cellular senescence through the CDK2-pRB1-Caspase3 axis

    Brain research28 Dec 2024

More on Apoptosis

Cellular senescence

downin human cells1

1 study

  1. Butylphthalide decreases cellular senescence in human cells.

    “we demonstrate that NBP ameliorate Aβ oligomer-induced cellular senescence and apoptosis”

    CellsAβ oligomer-induced cellular senescenceU87

    3-N-Butylphthalide alleviate Aβ-induced cellular senescence through the CDK2-pRB1-Caspase3 axis

    Brain research28 Dec 2024

More on Cellular senescence

Latest

Related