Bs@md

1. Bs@md decreases senescence-associated secretory phenotype (SASP) in mice.

   “suppressing SASP production, effectively disrupting the senescence-inflammation feedback loop”

   Animalsin OA microenvironment

   Synergistic targeting of senolytic and senomorphic action with dual-engineered biomimetic macrophage nanovesicles for mitigating osteoarthritis

   Bioactive materials·19 Jan 2026

More on Senescence-associated secretory phenotype (SASP)

1. Bs@md induces senescent chondrocyte apoptosis in mice.

   “inducing sCDs apoptosis and suppressing SASP production”

   Animalsin OA microenvironmentcartilage

   Synergistic targeting of senolytic and senomorphic action with dual-engineered biomimetic macrophage nanovesicles for mitigating osteoarthritis

   Bioactive materials·19 Jan 2026

1. Bs@md decreases inflammation in mice.

   “reduces cartilage degradation and inflammation”

   Animalsin ACLT-induced and naturally aged OA mice

   Synergistic targeting of senolytic and senomorphic action with dual-engineered biomimetic macrophage nanovesicles for mitigating osteoarthritis

   Bioactive materials·19 Jan 2026

More on Inflammation

1. Bs@md decreases cartilage degradation in mice.

   “reduces cartilage degradation and inflammation, and promotes cartilage homeostasis”

   Animalsin ACLT-induced and naturally aged OA mice

   Synergistic targeting of senolytic and senomorphic action with dual-engineered biomimetic macrophage nanovesicles for mitigating osteoarthritis

   Bioactive materials·19 Jan 2026