Bifidobacterium longum

2 papers1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: Edward Mallinckrodt, Jr. Foundation and 5 more

Animals1
Model organisms1

Outcomes

Lifespan

upin worms1

1 study

Bifidobacterium longum extends lifespan in worms.
“We identified two B. longum and B. infantis strains that most strongly increased lifespan and stress resistance.”
Model organisms
Human gut Bifidobacteria strains regulate host longevity via shared and divergent mechanisms in C. elegans
bioRxiv : the preprint server for biology17 Oct 2025Preprint

Latest

1 in 12 months

bioRxiv24 Nov

Human gut Bifidobacteria strains regulate host longevity via shared and divergent mechanisms in C. elegans

Preprint: experiments in wormsInterventions

Paper

Journal of Agricultural and Food Chemistry14 Nov

Probiotics Ameliorate Aging-Related Cognitive Impairments and Pathological Changes through Alleviating Telomere Attrition and Enhancing Mitochondrial Function in Senescence-Accelerated Mouse Prone 8 Mice

Experiments in miceProbiotics

Paper